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What Is Sufentanil?

Sufentanil is a synthetic opioid analgesic in the fentanyl analog family. It is 1000 times more potent than morphine and about 5–10 times more potent than fentanyl, making it one of the most powerful opioids used in clinical medicine. It is typically used in hospitals, especially during major surgery or for intensive care patients, and is not intended for general or unsupervised use.

When in powdered form, sufentanil appears as a white to off-white fine powder—but in medical settings, it is most often administered as an injectable solution or sublingual tablet.

Sufentanil Powder is associate Opioid Agonist. The mechanism of action of sufentanil is as a Full Opioid Agonist. Sufentanil is an opioid analgesic that’s used as an adjunct in anesthesia, in balanced anesthesia, and as a primary anesthetic agent. it’s administered by the intravenous, epidural and articulator routes. additionally referred to as Dsuvia, the sublingual type is employed for the management of acute pain in adults that is severe to warrant the utilization of an opioid analgesic in certified medically supervised attention settings, as well as hospitals, surgical centers, and emergency departments. thought is also created in the future for the utilization of the articulator type within the U.S. military in cases wherever physiological state is needed immediately.

IUPAC Name
N-[4-(methoxymethyl)-1-(2-thiophen-2-ylethyl)piperidin-4-yl]-N-phenylpropanamide

InChI
InChI=1S/C22H30N2O2S/c1-3-21(25)24(19-8-5-4-6-9-19)22(18-26-2)12-15-23(16-13-22)14-11-20-10-7-17-27-20/h4-10,17H,3,11-16,18H2,1-2H3

InChI Key
GGCSSNBKKAUURC-UHFFFAOYSA-N

Canonical SMILES
CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC3=CC=CS3)COC

Mechanism of Action

Sufentanil, like other opioids, works by binding to mu-opioid receptors in the central nervous system. This leads to:

• Inhibition of pain signals

• Profound sedation

• Euphoria (in some contexts)

• Respiratory depression (potentially fatal)

Its high potency allows for very small doses to achieve clinical effects, which also dramatically increases the risk of accidental overdose in non-medical contexts.

💊 Medical Uses

Sufentanil is used in carefully controlled settings for:

• Surgical anesthesia (as part of balanced anesthesia regimens)

• Postoperative pain management (especially in critical care)

• Sublingual tablets for severe acute pain in controlled environments (e.g., battlefield or emergency medicine in some cases).Buy Sufentanil Powder Europe , Purchase Sufentanil EU ,Sufentanil for sale Europe ,Order Sufentanil online Europe , Sufentanil research chemical Europe

chemical formula
C22H30N2O2S

Drug and medicine data
Drug Indication to Buy Sufentanil Powder Online
The indications for this drug are as follows: 1. As an analgesic adjunct in the maintenance of balanced general anaesthesia in patients who are intubated and ventilated. 2. As a primary anaesthetic agent for the induction associated maintenance of anaesthesia with one hundred pc chemical element in patients undergoing major surgical procedures, in patients who are intubated and ventilated, admire vessel surgery or neurosurgical procedures within the sitting position, to produce favorable cardiac muscle and cerebral oxygen balance or once extended operative ventilation is anticipated. 3. For epidural administration as an analgesic combined with low dose (usually 12.5 mg per administration) bupivacaine sometimes throughout labor and duct delivery 4. The articulator type is indicated for the management of acute pain in adults that’s severe to warrant the utilization of an opioid analgesic in certified medically supervised attention settings, as well as hospitals, surgical centers, and emergency departments.Buy Sufentanil Powder Europe , Purchase Sufentanil EU ,Sufentanil for sale Europe ,Order Sufentanil online Europe , Sufentanil research chemical Europe

Mechanism of Action
Sufentanil could be a synthetic, potent opioid with extremely selective binding to ?-opioid receptors [F2009]. These receptors are cosmopolitan within the human brain, spinal cord, and alternative tissues [A39636], [A39637]. In general, opioids decrease cAMP (affecting neural communication pathways), decrease neurochemical release, and cause membrane hyperpolarization, all of that contribute to the relief of painful symptoms [A39637]. narcotic receptors are including G-protein receptors and performance as each positive and negative regulators of conjugation neural transmission via G-proteins that activate effector proteins. Binding of the opiate receptor leads to the exchange of GTP for gross domestic product on the G-protein complex. because the effector system is adenylate cyclase and cAMP, placed at the inner surface of the plasma membrane, opioids decrease animate thing cAMP by inhibiting adenylate cyclase. the discharge of sensitive neurotransmitters admire substance P, GABA, dopamine, acetylcholine, and norepinephrine is then strangled [A39637]. Opioids shut N-type voltage-operated metal channels (OP2-receptor agonist), additionally preventing neurotransmitter release [A39637]. Sufentanil and alternative opioids open calcium-dependent inside rectifying metal channels, leading to hyperpolarization and reduced neural excitability [A39636], [A39637].