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What is 5F-QUPIC
5F-BB-22, also known as 5F-QUPIC, is a synthetic cannabinoid a type of lab-made chemical designed to mimic the effects of THC, the main psychoactive compound found in cannabis. It belongs to the indole-based class of synthetic cannabinoids and is structurally similar to BB-22, with a fluorine atom attached to its pentyl chain (hence the “5F” prefix).
These compounds were initially synthesized for research purposes, specifically to study the endocannabinoid system. However, many synthetic cannabinoids, including 5F-BB-22, found their way into the recreational drug market and have been sold under misleading names such as “herbal incense,” “Spice,” or “K2.”
Buy 5F-BB22 Crystal is an analytical reference material that is structurally categorized as a synthetic cannabinoid (CB). It is a full agonist of human CB1 and CB2 receptors (pEC50s = 8.55 and 7.97, respectively).1,2 5-fluoro PB-22 potently and dose-dependently induces hypothermia and reduces heart rate in rats, mimicking the in vivo effects of ?9-THC.1 This product is intended for research and forensic applications.
Pharmacology
5F-BB22 acts as a full agonist with a binding affinity of 1.94 nM at CB1 and 0.266 nM at CB2 cannabinoid receptors.
Those of you who are in the market for high-grade synthetic cannabinoid powder or Crystals for sale can easily find it at croweed. The purity of our products is without equal, not to mention how varied our range of supplements is. It includes much more than just traditional THC and CBD so that you can make your research complete.
Although they are synthetic, our cannabinoids have a close affinity with natural compounds that occur in the cannabis plant. Not only do they release their effects in the same way (by interacting with cannabinoid receptors), but they are also associated with high selectivity and little to no toxicity. Besides, our cannabinoids are proven to trigger the same nervous system responses, which is especially important for research in the area.
Chemical Structure and Classification
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Full name: 1-(5-Fluoropentyl)-1H-indole-3-carboxylic acid [1-(quinuclidin-3-yl) methyl] ester
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Chemical Class: Synthetic cannabinoid (Indole-based)
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Molecular Formula: C25H31FN2O2
5F-BB-22 acts as a full agonist at the CB1 and CB2 receptors in the body’s endocannabinoid system, which regulates mood, appetite, pain sensation, and memory. Compared to natural THC, which is a partial agonist, compounds like 5F-BB-22 often produce much stronger and more unpredictable effects.
Mechanism of Action
5F-BB-22 binds strongly to cannabinoid receptors (especially CB1, located primarily in the brain), leading to powerful psychoactive effects. Due to its full agonist nature, the effects can be significantly more intense than natural cannabis, often resulting in harmful outcomes such as:
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Extreme anxiety
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Hallucinations
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Elevated heart rate
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Loss of consciousness
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Seizures
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