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4-Phenylfentanyl is a synthetic opioid and a chemical analogue of fentanyl, a potent pharmaceutical used in pain management. While fentanyl itself has legitimate medical uses, analogues like 4-Phenylfentanyl are often synthesized and distributed illicitly. Due to their extreme potency and the unpredictable nature of their effects, such substances pose significant health and legal risks. This article provides an educational overview of 4-Phenylfentanyl powder, including its chemistry, pharmacology, potential uses, legal considerations, and public health concerns.

Buy 4-Phenylfentanyl Powder (4-Phenylfentanyl) is an opioid analgesic that is a derivative of fentanyl. It was developed during the course of research that ultimately resulted in super-potent opioid derivatives such as carfentanil, though it is a substantially less potent analogue. 4-Phenylfentanyl is around eight times the potency of fentanyl in analgesic tests on animals, but more complex 4-heteroaryl derivatives such as substituted thiophenes and thiazoles are more potent still, as they are closer bioisosteres to the 4-carbomethoxy group of carfentanil.

Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.

Pharmacology and Effects

As an opioid receptor agonist, 4-Phenylfentanyl primarily binds to mu-opioid receptors in the central nervous system. This interaction results in:

• Analgesia (pain relief)

• Sedation

• Euphoria

• Respiratory depression

• Physical dependence

While the exact potency of 4-Phenylfentanyl compared to fentanyl is not fully documented, anecdotal reports and limited scientific literature suggest it is highly potent and capable of producing significant physiological effects even in small doses. Like other fentanyl analogues, it carries a high risk of overdose, especially when mixed with other central nervous system depressants like alcohol or benzodiazepines.

Chemical and physical data
Formula: C28H32N2O

Molar mass: 412.577 g·mol?1

CAS
120448-97-7

InChI
InChI=1S/C28H32N2O/c1-2-27(31)30(26-16-10-5-11-17-26)28(25-14-8-4-9-15-25)19-22-29(23-20-28)21-18-24-12-6-3-7-13-24/h3-17H,2,18-23H2,1H3

InChI Key
BXCJXJLHYMWMQU-UHFFFAOYSA-N

Canonical SMILES
CCC(=O)N(C1=CC=CC=C1)C2(CCN(CC2)CCC3=CC=CC=C3)C4=CC=CC=C4

Registry Number
Linked Records

Compounds: 313,587
Substances: 390,235
Classification (Parent Nodes)

ChemIDplus Chemical Information Classification
Shipping & Storage Information
Storage: -20°C
Shipping: Room Temperature in continental US; may vary elsewhere
Stability: ? 2 years

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