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What is LSD?

Lysergic acid diethylamide, commonly known as LSD, is a potent psychedelic drug that alters perception, mood, and consciousness. It is one of the most powerful hallucinogenic substances known, with effects often experienced at doses as small as 20–100 micrograms (µg).

LSD is synthetic, but its origin lies in a naturally occurring compound: lysergic acid, derived from ergot, a fungus that grows on rye and other grains.

📜 History

1938 – Synthesized by Swiss chemist Albert Hofmann at Sandoz Laboratories
1943 – Hofmann accidentally ingested LSD and became the first person to experience its psychedelic effects
1950s–1960s – LSD was explored in psychiatry and psychotherapy
1960s–70s – Became associated with counterculture and anti-establishment movements
1970 – Classified as a Schedule I drug in the U.S. under the Controlled Substances Act (illegal, high abuse potential, no accepted medical use)

🔬 Chemical Structure

Full Name: Lysergic acid diethylamide
Molecular Formula: C₂₀H₂₅N₃O
Structure: Derived from the ergoline family of compounds, with a diethylamide group added to lysergic acid
Potency: Active at doses as low as 20–30 µg
Duration: Effects last 8 to 12 hours