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  • CAS Number: 18268-65-2 (unofficial)

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Dibutylone (chemical name: 1-(1,3-benzodioxol-5-yl)-2-(dibutylamino)propan-1-one) is a synthetic stimulant and entactogen that falls under the cathinone class of compounds. Known for its similarity to methylone and ethylone, it has been explored primarily in chemical research.

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  • Molecular Formula: C12H15NO3

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Methylone is the β-keto analogue of MDMA, differing by a ketone group that impacts its behavioral and chemical properties. It acts as a potent serotonin‑norepinephrine‑dopamine releasing agent, though with roughly one-third the activity at serotonin transporters compared to MDMA. This gives it a quicker onset (~30 minutes) and shorter duration (~2–3 hours) of effects Wikipediaanchoredrc.com.Preclinical studies confirm its stimulant nature and rewarding effects in animals, as well as potential liver cytotoxicity

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Our Methylone Crystal is intended strictly for scientific and forensic research purposes. Current avenues of investigation include:

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  • Therapeutic potential for psychiatric conditions like PTSD (e.g., TSND‑201 in phase 2 trials) Wikipediaanchoredrc.com

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Safety, Risks & Observations

Users and researchers should note that methylone remains a research chemical, and its long-term impact is not fully understood. Known risks include:

Regulatory & Legal Landscape

Methylone is regulated in many countries:

  • United States: Classified as Schedule I controlled substance since April 2013 WikipediaGovInfo

  • United Kingdom: Controlled under Class B regulations Drugs-Forum

  • Germany, Sweden, Netherlands, New Zealand, and others: Strict controls under analog or specific drug scheduling laws Drugs-ForumWikipedia

Before procuring, be sure to confirm your jurisdiction’s current regulatory status.

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Pentylone, also known as β‑Keto‑Methylbenzodioxolylpentanamine, βk‑MBDP, or methyl­enedioxy­pentedrone, is a potent stimulant research chemical belonging to the substituted cathinone class. Originally synthesized in the 1960s, it resurfaced in the early 2010s as part of designer “legal highs,” frequently appearing in mixtures like NRG‑1 and NRG‑3.

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Pentylone acts as a serotonin-norepinephrine-dopamine reuptake inhibitor (SNDRI) and also functions as a serotonin-releasing agent, giving it a unique pharmacological

Onset & Duration:

  • Insufflation: ~10 minutes

  • Oral ingestion: ~20–40 minutes

  • Overall duration: Approximately 3–4 hours, with potential after-effects lasting up to 6 hours.

  • Notable Risks:
    Though chemical effects can resemble those of MDMA or other stimulants, higher doses are associated with severe paranoia, agitation, insomnia, prolonged stimulation, and even cardiovascular strain. Reports highlight how a standard MDMA dose substituted with Pentylone can result in hours—or even days—of adverse effects like severe agitation or psychosis.

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    Pentylone’s distinctive pharmacological profile makes it a subject of interest for neuropharmacology studies and synthetic cathinone research. Its measurable reuptake inhibition across multiple neurotransmitters provides valuable insight, especially when contrasted with human data lacking in current literature.

  • Pentylone is a stimulant developed in the 1960s. It is a substituted cathinone that has been identified in some samples of powders sold as “NRG-1”, along with varying blends of other cathinone derivatives including flephedrone, MDPBP, MDPV, and 4-MePPP. It was also found in combination with 4-MePPP being sold as “NRG-3”. Reports indicate side effects include paranoia, agitation, and insomnia, with effects lasting for several days at high doses.Pentylone acts as a serotonin–norepinephrine–dopamine reuptake inhibitor (SNDRI) and a serotonin releasing agent.

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Dibutylone, also commonly referred to as bk-DMBDB, Buy Dibutylone Crystals Online, is a stimulant drug of the amphetamine, phenethylamine, and cathinone drug classes. These types of drugs feature a phenethylamine core with an alkyl group attached to the alpha carbon, and a ketone group attached to the beta carbon. Cathinone occurs naturally in the plant khat, the leaves of which are often chewed as a recreational drug. Looking to buy Dibutylone Crystals Online? You are in the right place.

what is Dibutylone?

Dibutylone (also known as bk-DMBDB) is a synthetic cathinone derivative and part of the substituted phenethylamine class. It has been used in analytical and forensic chemistry for the study of psychoactive compounds. Structurally related to compounds like butylone and methylone, Dibutylone appears as a white to off-white crystalline powder.

While not approved for human consumption, it is widely used in controlled laboratory environments for scientific research.

Disclaimer: Dibutylone is a research chemical. It is not intended for human or veterinary use and should only be handled by qualified professionals in licensed labs.

Dibutylone is a potentially psychotropic designer drug. It is structurally related to methylone, a designer drug that has been detected in products like bath salts, plant food, and tablets. However, the effects of a chemical substance such as this are still unknown in regards to organic specimens, including human subjects. It is considered to be a biochemical with widespread applications in Mass Spectrometry. Therefore, those looking to buy Dibutylone might intend to use it in research areas like Neuroscience and Forensic Science.

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Some more technical information on this chemical substance includes:

Formal Name: 1-(1,3-benzodioxol-5-yl)-2-(dimethylamino)-1-butanone, monohydrochloride

Formula Weight: 271.7

Purity: Greater than or equal to 98%

Formulation: A crystalline solid

Storage: -20°C

Stability: Typically no less than two years worth of stability

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While the effects of this type of chemical substance on human subjects is widely unknown, many have started to buy Dibutylone for use as a recreational designer drug. Drugs of this type are typically purchased with the hopes of achieving euphoric experiences, both physically and cognitively. Many seek alternatives like this in comparison to more commonly obtained prescription drugs or over the counter medications in the hopes of achieving a stronger experience. Some also seek these alternatives attempting to find a drug that offers these experiences with fewer of the negative side effects that other common drugs might yield.

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In comparison to other drugs like this, many users find that the experience is mild at best, only resulting in a slight euphoric experience. Only a very small number of users have cited this, however, with the others mostly citing no change in mental state whatsoever. Some did note a pleasant rush, more openness when it comes to sharing emotions and thoughts, and a positive lift in mood. These users have cited ingesting nasally to be the best experience, however they have also ingested the chemical substance orally by mixing with water and drinking the resultant substance.

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Drugs like this typically yield certain negative side effects as well, including occasional nausea and even hallucinations. Some common side effects users of Dibutylone have cited include feelings of a heavy chest, an increase in heart rate, and constipation. Many compare it to other MDMA chemical substances, except they claim this substance has more controllable effects in comparison to others.

All products, including the substance Dibutylone, are sold as research specimens exclusively and are not for human consumption under any circumstances. Due to the lack of research on organic specimens, including human subjects, the effects are widely unpredictable and it should only be used as a research chemical.

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Buy Methylone Crystal (also known as “3,4-methylenedioxy-N-methylcathinone“, “MDMC“, “?k-MDMA” and by the slang term “M1“) is an empathogen and stimulant psychoactive drug. It is a member of the substituted amphetamine, substituted cathinone and substituted methylenedioxyphenethylamine classes.

Methylone is the substituted cathinone analog of MDMA and the 3,4-methylenedioxy analog of methcathinone. The only structural difference of methylone with respect to MDMA is the substitution of 2 hydrogen atoms by 1 oxygen atom in the ? position of the phenethylamine core, forming a ketone group.

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Methylone was first synthesized by the chemists Peyton Jacob III and Alexander Shulgin in 1996 for potential use as an antidepressant. Methylone has been sold for recreational use, taking advantage of the absence of legal prohibition of this compound in many countries.

Resemblance to MDMA

Structural similarities between some amphetamine-like stimulants and their 3,4-methylenedioxy- derivatives.
Left: amphetamine, methamphetamine and methcathinone.
Right: MDA, MDMA, and methylone
Methylone substitutes for MDMA in rats trained to discriminate MDMA from saline. Methylone does not substitute for amphetamine or for the hallucinogenic DOM in animals trained to discriminate between these drugs and saline. Further, also in common with MDMA, methylone acts on monoaminergic systems. In vitro, methylone has one third the potency of MDMA at inhibiting platelet serotonin accumulation and about the same in its inhibiting effects on the dopamine and noradrenaline transporters.

In spite of these behavioral and pharmacological similarities between methylone and MDMA, the observed subjective effects of both drugs are not completely identical. Alexander Shulgin wrote of the former.

[Methylone] has almost the same potency of MDMA, but it does not produce the same effects. It has an almost antidepressant action, pleasant and positive, but not the unique magic of MDMA.

Pharmacology

Methylone acts as a mixed reuptake inhibitor/releasing agent of serotonin, norepinephrine, and dopamine. In comparison to MDMA, it has approximately 3x lower affinity for the serotonin transporter, while its affinity for the norepinephrine and dopamine transporters is similar. Notably, methylone’s affinity for the vesicular monoamine transporter 2 (VMAT2) is about 13x lower than that of MDMA. The results of these differences in pharmacology relative to MDMA are that methylone is less potent in terms of dose, has more balanced catecholaminergic effects relative to serotonergic, and behaves more like a reuptake inhibitor like methylphenidate than a releaser like amphetamine; however, methylone has relatively robust releasing capabilities, perhaps due to its ability to phosphorylate the monoamine transporters being similar in potency relative to MDMA.

Pharmacokinetics

The two major metabolic pathways in mammals for methylone are N–demethylation to methylenedioxycathinone (MDC), and demethylation followed by O–methylation of the 3- or 4-hydroxy group to 4-hydroxy-3-methoxymethcathinone (HMMC) or 3-hydroxy-4-methoxymethcathinone (3-OH-4-MeO-MC). When 5 mg/kg of methylone was administered to rats, it was found that around 26% was excreted as HMMC within the first 48 hours (less than 3% excreted unchanged).

Commercial distribution

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Analysis of “Explosion” has confirmed that the active ingredient is methylone. Many other formulations marketed as household chemicals, as well as the pure powder, have been sold.

Etymology
“Methylone” is also a trademarked brand name for an injectable form of methylprednisolone, a corticosteroid hormone used to treat arthritis and severe allergic reactions; hence, methylone may be confused with it. Aside from context, they can be distinguished by the fact that the name will usually be capitalized when referring to the prescription drug.

A proposed alternate name is ?k-MDMA, or beta-keto-MDMA. While this nomenclature has not caught on because the name “methylone” became widely used before the conflicting Methylone trademark was noticed, the analogous names for related chemicals ?k-MDEA and ?k-MBDB have become the established names for those substances.

Chemical and physical data:
Formula: C11H13NO3

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